Deep monographs
Monographs
A monograph supplies the depth a term or question needs: definition and scope, key distinctions, history, the philosophical or technical account, biomedical and nuclear medicine relevance, disagreements, and references.
20 assigned. 7 drafted (unreviewed), 13 as writing briefs, 0 reviewed. Every page states its own state.
Ontology
Before we can agree about a thing, we have to agree that it is a thing, and what kind of thing it is.
Epistemology
A reading of a scan is a claim to know something. What entitles the reader to make it?
Taxonomy
What does a hierarchy express?
Thesaurus
How are words connected for retrieval?
Controlled vocabularies
What does controlling a vocabulary achieve?
Knowledge graphs
A graph is a way of writing down who is connected to what. It is not a way of knowing whether the connection is real.
Description logics
What follows from a formal definition?
Semantic web standards
How do identifiers and representations work together?
SNOMED CT and the NucLex niche
A clinical terminology of several hundred thousand concepts already exists. The question is what a nuclear medicine lexicon should reuse, what it should add, and how it should keep the two apart.
FHIR terminology resources
CodeSystem, ValueSet, and ConceptMap are the three containers that carry meaning between systems. They are not the meaning itself.
Semantic interoperability
When do systems preserve intended meaning?
Provenance and evidence
Where did a statement come from?
Precision nuclear oncology
An individualized question is answered from thousands of records, in several formats, made at different times, by people who did not know the question would be asked.
Radiopharmaceutical identity
What object must be described consistently?
Biodistribution and pharmacokinetics
Where does an agent go over time?
Molecular targeting
What must be known about a target?
Theranostic digital twins
What would a twin need to represent and validate?
Interactional ontology
Knowing what A is and what B is does not tell you what A does to B. The interaction needs a record of its own.
Human review of machine proposals
Who decides whether a proposal is accepted?
Model-ready knowledge exchange
What must travel with a parameter?