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Lexicon · Tools and roadmap

Lexicon entryDraftNX-C045

Interactional ontology

Fully specified name: Interactional ontology (concept)

The proposed NucLex representation of interactions as explicit objects with participants, context, and evidence.

Scope note
A project design direction rather than an implemented standard.
Synonyms
None recorded as true synonyms in this context.
Monograph
Interactional ontology (draft)
External mappings
None recorded. In W0 no mapping to SNOMED CT® or any external authority is asserted for this entry. A future mapping record will carry source system, identifier, version, relation type, evidence, author, confidence where meaningful, and review state.
Formal status
Editorial entry only. It is not part of any released ontology and a prose edit here changes no formal definition.

Draft. This entry is an unreviewed draft. Its sources have not been checked by a named person and no domain reviewer has approved it. Treat every claim as provisional.

Notes

Most ontologies describe things and the relationships between them as labeled links: this ligand binds that receptor, this radionuclide is a component of that agent. A link of that kind is a single assertion with no room for the conditions under which it holds, how strongly, or on what evidence. Interactional ontology is the NucLex proposal to make the interaction itself a first-class object. An interaction record names its participants and their roles, the context in which it was observed (biological system, method, conditions, time), any parameters that characterize it (an affinity, a rate), the uncertainty of those parameters, and the evidence and provenance behind the whole.

The motivation is practical. A physician asking whether a target is reachable, a radiochemist comparing two labeled molecules, and a modeler assembling a compartment model all need the same interaction facts, but with different qualifiers attached. A bare link serves none of them well. An interaction object can carry all the qualifiers and still be reduced to a simple link when a simple view is wanted.

Related ideas exist elsewhere: reified relationships in knowledge graphs, event-centered models in biology, and reaction records in model exchange formats. NucLex does not claim priority over these.

This is a design direction, not an implemented standard. No NucLex interaction schema has been released, and the term describes the project's proposal unless a cited external use is named.